LOCATION

149 Emerald Street, Suite O, Keene, NH 03431

M-Th 8-5, F 8-12

aged cloves of garlic

Aged Garlic Extract

It's an apt coincidence that the abbreviation for aged garlic extract is "age." as the body gets older, it may need help with the processes that maintain good health. And AGE is ready to step in.

What's different about AGE?

Garlic not only provides a tasty addition to meals but also boasts many health benefits, including "antioxidants that support the body's protective mechanisms against oxidative damage," according to nutritionist Joe Leech, MSc. This is important as the body ages, as is protecting immunity. "Garlic supplements are known to boost the function of the immune system," says Leech.

Aged garlic extract boosts health benefits, thanks to a proprietary preparation method, in which organically grown garlic is cleaned, sliced, and aged in stainless-steel containers for 20 months. This process results in odorless and more bioavailable compounds.

Benefits of Aged Garlic Extract

Taken together, cardiovascular diseases are the world's leading cause of death. New studies show the protective effects of AGE on cardiovascular health, both with and without the risk factors that come with having diabetes.

AGE for Cardiovascular& Health

A randomized, doubleblind, placebo-controlled study found a significant inhibition of the progression of coronary artery calcification (atherosclerosis) in a group of adults who took 2,400 milligrams of aged garlic extract daily for one year, a result not found in the placebo group.

Other benefits to the AGE group included risk factors for cardiovascular events, such as heart attack and stroke:

  • lower blood pressure
  • fasting blood glucose
  • inflammatory markers

AGE for People with Diabetes

Heart disease is responsible for the deaths of nearly 70 percent of adults over the age of 65 who have diabetes, according to the American Heart Association. But the AHA considers diabetes to be a controllable risk factor.

Three new studies offer hope to those with diabetes who want to lower their risk of cardiovascular disease.

Coronary Artery Plaque and Endothelial Cells

A small randomized, double-blind, placebo-controlled study looked at coronary artery plaque in people with diabetes. While the group that received AGE exhibited a 29 percent reduction in unstable, fatty plaque over the course of the study, the placebo group saw a 57 percent progression in plaque.

Endothelial cells, which line the circulatory system, control vascular relaxation and contraction and play a role in blood clotting and platelet adhesion.

Cardio-Ankle Vascular Index

Paving the way for further research into the effects of AGE on improving vascular endothelial function, a small, three-month study showed a larger reduction in the cardio-ankle vascular index (CAVI) of Type 2 diabetes patients who took AGE than in that of the placebo group. CAVI measures arterial stiffness from the  ascending aorta to the ankle arteries.

Ventricular Myocardial Mass

The third study looked at left ventricular myocardial mass (LVM), an increase in which is an indicator of poor cardiac outcomes.

After a year, researchers observed a trend toward a decreased LVM in the group taking AGE, and no change in the placebo group.

The researchers suggest further trials with larger study populations and longer duration to understand the trend better.

Sources

"11 proven health benefits of garlic" by Joe Leech, www.healthline.com, 6/28/18

"Aged garlic extract reduces left ventricular myocardial mass in patients with diabetes: A prospective randomized controlled double-blind study" by E. Hutchins et al., Experimental and Therapeutic Medicine, 12/27/19

"Aged garlic extract reduces low attenuation plaque in coronary arteries of patients with diabetes: A randomized, double-blind, placebo-controlled study" K. Shaikh et al., Experimental and Therapeutic Medicine, 2/20

"Short-term impact of aged garlic extract on endothelial function in diabetes: A randomized, double-blind, placebo-controlled trial" by S. Hamal et al., Experimental and Therapeutic Medicine, 12/27/19

"Cardiovascular disease and diabetes," American Heart Association, www.heart.org

"Cardiovascular diseases (CVDs):Key facts," Word Health Organization, www.who.int, 5/17/17

"The effect of aged garlic extract on the atherosclerotic process . . . ," by M. Wlosinska et al., BMC Complementary Medicine and Therapies, 4/29/20